Quantitative of murine mammary tumor virus-related RNA in mammary tissues of low- and high-mammary-tumor-incidence mouse strains
نویسندگان
چکیده
منابع مشابه
Mouse mammary tumor virus genome expression in chemical carcinogen-induced mammary tumors in low- and high-tumor-incidence mouse strains.
Involvement of mouse mammary tumor virus (MMTV) in 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis was investigated in low- (BALB/c) and high- (BALB/cfC3H) mammary-tumor-incidence mouse strains. Both strains contain endogenous MMTV integrated into the cellular genome. Additionally, BALB/cfC3H mice are infected with exogenous MMTV-S which is responsible for a higher incidence...
متن کاملUltrastructural and quantitative studies of mammary tumor virus production in cultured mouse mammary tumor cells.
A whole-cell-mounting technique was successfully applied to the study of mouse mammary tumor virus budding from cells in tissue culture. The technique permitted the visualiza tion of ultrastructural detail, including the cores and the surface spikes of budding virions. The latter are difficult to discriminate in thin sections. Budding mammary tumor virus was compared with budding murine leukemi...
متن کاملUltrastructural and Quantitative Studies of Mammary Tumor Virus Production in Cultured Mouse Mammary Tumor Cells
A whole-cell-mounting technique was successfully applied to the study of mouse mammary tumor virus budding from cells in tissue culture. The technique permitted the visualiza tion of ultrastructural detail, including the cores and the surface spikes of budding virions. The latter are difficult to discriminate in thin sections. Budding mammary tumor virus was compared with budding murine leukemi...
متن کاملCharacteristics of mammary tumor cultures from four mouse strains infected with mammary tumor virus.
The morphology and production of oncornaviruses in primary cell and explant mammary adenocarcinoma cultures derived from C3Hf, BALB/cNIV, BALB/cfC3H, and C3H mice were characterized. Cultures from the four mouse strains were morphologically similar; they were all epithelial and formed hemicysts and mounds. However, the numbers of cells containing mammary tumor virus (MTV) antigens and the produ...
متن کاملIn vitro production of mouse mammary tumor virus in a mouse mammary tumor ascites line.
An ascites line derived from a spontaneous mouse mammary carcinoma produces, on explantation and cultivation in vitro, large amounts of oncornavirus particles. The biochemical, biophysical, and electron microscopic characteristics of the virions are described. Molecular hybridization and immunological methods identify these virions as mouse mammary tumor virus.
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1981
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.40.1.87-95.1981